Is IXEMPRA Right for Me?

IXEMPRA® (ixabepilone) is a prescription medicine used to treat locally advanced or metastatic breast cancer when certain other medicines have not worked or no longer work. IXEMPRA can be used alone or with another cancer medicine called Xeloda® (capecitabine).

Locally advanced means the cancer is large and/or has spread from where it started to nearby areas such as the skin or chest wall or to lymph nodes in the armpit area. It has not spread to distant organs. Metastatic means the cancer has spread from where it started to distant parts of the body.

Is IXEMPRA right for me?

See the examples below, which represent the qualities of patients enrolled in IXEMPRA clinical trials. Talk to your doctor to find out if IXEMPRA is right for you.

Patient 1

Patient has met all of these conditions:

  • Patient has not yet received treatment for metastatic disease.
  • Patient received BOTH an anthracycline AND a taxane during the first phase of chemotherapy (adjuvant or neoadjuvant therapy).
  • Patient’s disease came back (recurred) within 6 months of the last dose of anthracycline (anthracycline-resistant).
  • Patient’s disease came back (recurred) within 12 months of the last dose of taxane (taxane-resistant).

IXEMPRA plus Xeloda

Patient 2

Patient has met all of these conditions:

  • Patient received at least one treatment for metastatic disease.
    • Prior treatment must have included an anthracycline and a taxane OR just a taxane if treatment with an anthracycline for metastatic disease was not an option.
  • Patient had disease growth within 3 months of the last dose of anthracycline, or the doctor decided the patient should no longer receive an anthracycline.
  • Patient had disease growth within 4 months of the last dose of taxane.

IXEMPRA plus Xeloda

Patient 3

Patient has met the following condition:

  • Patient received several medicines to treat metastatic breast cancer. These medicines must have included anthracyclines, taxanes, and Xeloda. All of these medicines either did not work or failed to control the disease.

IXEMPRA plus Xeloda

Hypothetical patient cases based on patients enrolled in IXEMPRA clinical trials.

Talk to your doctor to find out if IXEMPRA is right for you.

Indications and Important Safety Informationexpand

What is IXEMPRA® (ixabepilone)?

IXEMPRA is used alone or with another cancer medicine called capecitabine to treat locally advanced breast cancer or breast cancer that has spread to other parts of the body (metastatic) when certain other medicines have not worked or no longer work. It is not known if IXEMPRA is safe and effective in children.

Important Safety Information about IXEMPRA

Your healthcare provider should do blood tests to check your liver function before you begin receiving IXEMPRA and as needed while you are receiving IXEMPRA. If blood tests show that you have liver problems, do not receive injections of IXEMPRA along with the medicine capecitabine. Taking these two medicines together if you have liver problems increases your chance of serious problems. These include serious infection and death due to a very low white blood cell count (neutropenia).

You should not have your injection of IXEMPRA if you:

Before you receive IXEMPRA, tell your healthcare provider about all of your medical conditions, including if you:

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. IXEMPRA and certain other medicines may affect each other causing side effects. IXEMPRA may affect the way other medicines work, and other medicines may affect how IXEMPRA works. Know the medicines you take. Keep a list of your medicines with you to show your healthcare provider.

How will I receive IXEMPRA?

What should I avoid while receiving IXEMPRA?

IXEMPRA may cause serious side effects. Tell your healthcare provider right away if you have any of the following while taking IXEMPRA:

The most common side effects of IXEMPRA when used alone or with capecitabine may include:

IXEMPRA may cause fertility problems in females and males, which may affect your ability to have children. Talk to your healthcare provider if you have concerns about fertility.

If you have any questions about your health or your medicines, talk with your healthcare provider.

Click here to see the Full Prescribing Information, including boxed WARNING regarding liver disease.