Your healthcare provider should do blood tests to check how well your liver is working before you begin treatment with IXEMPRA and as needed during treatment. If blood tests show that you have liver problems, do not receive injections of IXEMPRA along with capecitabine. If you have liver problems, taking these medicines together could increase your chance of serious infection and death due to a very low white blood cell count (neutropenia).

You should not have your injection of IXEMPRA if you are allergic to medicines that contain Cremophor® EL* (polyoxyethylated castor oil) or if you have a low white blood cell count or a low platelet count. Continue to full Important Safety Information below

IXEMPRA a prescription medicine, used to treat breast cancer when certain medicines have not worked or no longer work can be used alone or with capecitabine.

Resources

The Internet can be a great resource for finding information about metastatic breast cancer and for connecting with other women who understand what you are going through. But the number of Web sites on the Internet can be overwhelming. Listed below are some Web sites that can provide you with information and support.

American Cancer Society www.cancer.org 800-ACS-2345 (800-227-2345)

The Breast Cancer Fund www.breastcancerfund.org 866-760-8223

Breast Cancer Network of Strength www.networkofstrength.org

CancerCare, Inc. www.cancercare.org 800-813-HOPE (800-813-4673)

Metastatic Breast Cancer Network www.mbcnetwork.org 888-500-0370

National Breast Cancer Coalition www.natlbcc.org 800-622-2838

National Comprehensive Cancer Network www.nccn.com 215-690-0300

National Cancer Institute www.cancer.gov 800-4-CANCER (800-422-6237)

Bristol-Myers Squibb Company does not endorse and is not responsible for the content of any of the listed Web sites or the services provided by these organizations. This is not an exhaustive list of resources.

What Is IXEMPRA® (ixabepilone)?

IXEMPRA is a prescription medicine used to treat locally advanced or metastatic breast cancer following certain treatments. IXEMPRA can be used alone or with another cancer medicine called Xeloda® (capecitabine).

IXEMPRA is a trademark of Bristol-Myers Squibb Company.
*Cremophor is a registered trademark of BASF AG.
Xeloda is a registered trademark of Roche Laboratories.
© 2010 Bristol-Myers Squibb, Princeton, New Jersey 08543 U.S.A. All rights reserved.

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Chemotherapy

A type of cancer treatment that uses certain medicines to destroy cancer cells. It can also harm healthy cells

Breast Cancer

A type of cancer treatment that uses certain medicines to destroy cancer cells. It can also harm healthy cells

Anthracycline

A type of medicine that damages the DNA in cancer cells, causing them to die

Anthracycline

A type of medicine that damages the DNA in cancer cells, causing them to die

Locally advanced

Cancer that has spread from the breast to nearby tissue or lymph nodes

Lymph nodes

Small masses of tissue that are an important part of the immune system. The lymph nodes act as filters that trap harmful things in the body

Metastatic

Cancer that has spread from the breast to other parts of the body

Preauthorization

When the insurance company decides if a treatment is medically necessary for the patient and will be paid for by the insurance company

Taxane

A type of medicine that stops cancer cells from dividing

Locally advanced

Cancer that has spread from the breast to nearby tissue or lymph nodes

Metastatic

Cancer that has spread from the breast to other parts of the body

Locally advanced

Cancer that has spread from the breast to nearby tissue or lymph nodes

Locally advanced

Cancer that has spread from the breast to nearby tissue or lymph nodes

Locally advanced

Cancer that has spread from the breast to nearby tissue or lymph nodes

Metastatic

Cancer that has spread from the breast to other parts of the body

Taxane

A type of medicine that stops cancer cells from dividing

Anthracycline

A type of medicine that damages the DNA in cancer cells, causing them to die

Lymph nodes

Small masses of tissue that are an important part of the immune system. The lymph nodes act as filters that trap harmful things in the body