IXEMPRA^® (ixabepilone) Used With Xeloda

IXEMPRA was studied in 752 women with locally advanced or metastatic breast cancer that continued to spread after treatment with an anthracycline and a taxane. Women received either IXEMPRA and Xeloda or Xeloda alone.

The progression of cancer was slowed for a longer period of time in women receiving IXEMPRA and Xeloda (about 6 months) than it was in women receiving Xeloda alone (about 4 months).

IXEMPRA may be a next step when the cancer has continued to grow after treatment with an anthracycline and a taxane. It is important to remember that everyone’s cancer is unique. Individual results may vary. Your healthcare provider can answer questions you may have about IXEMPRA in clinical trials.

Important Safety Information

Treatment with IXEMPRA may cause serious side effects, including neuropathy, low white blood cell count, allergic reactions, and harm to an unborn baby. This may not be a complete list of all side effects you might experience. Learn about the serious side effects of IXEMPRA.

The most common side effects of IXEMPRA, when used alone or with Xeloda, may include:

• Tiredness
• Loss of appetite
• Problems with your toenails and fingernails
• Hair loss
• Fever
• Decreased red blood cell count (anemia)
• Joint and muscle pain
• Headache
• Decreased platelet count (thrombocytopenia)
• Nausea, vomiting, diarrhea, constipation, and abdominal pain
• Sores on the lip, in the mouth, and in the throat
• Tender, red skin on the palms of the hands and the soles of the feet (hand-foot syndrome). It may look like a sunburn. The skin may also become dry and peel or may feel numb and tingly

Learn more about possible side effects of IXEMPRA.

Learn about IXEMPRA used alone.